Investigating the Role of HuR's Binding Partner PHAPI in Apoptosome Stimulation

研究 HuR 结合伙伴 PHAPI 在凋亡体刺激中的作用

• 批准号: 252440
• 负责人: Macri Angelo M
• 金额: $ 1.27万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-02-01 至 2013-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=252440&lang=en
• 关键词: Apoptosis; Electrophoretic Mobility Shift Assay; Fractionation; Immunofluorescence; Immunoprecipitation; Intracellular Trafficking; Mass Spectrometry; Rna Analysis; Western Blotting

Apoptosis, also known as organized cell death, has been shown to be heavily regulated in healthy cells, and excess of this organized death (such as in neurodegenerative disorders) could have disastrous consequences. On the other hand, resistance to apopto

细胞凋亡，也被称为有组织的细胞死亡，已被证明在健康的细胞中受到严格的调控，超过这种有组织的死亡(如在神经退行性疾病中)可能会产生灾难性的后果。另一方面，对Aopto的抗药性