课题基金 / 基金详情

Identification and characterization of Protein Phosphatase 1 interactors by affinity-purification and quantitative mass spectrometry using differential metabolic labeling

使用差异代谢标记通过亲和纯化和定量质谱法鉴定和表征蛋白磷酸酶 1 相互作用物

批准号：

253397

负责人：

Freele Emily A

金额：

$1.27万

依托单位：

University of Ottawa

依托单位国家：

加拿大

项目类别：

Studentship Programs

财政年份：

2012

资助国家：

加拿大

项目状态：

已结题

起止时间：

2012-02-01 至 2013-02-01

来源：

https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=253397&lang=en

关键词：

Affinity Purification Cancer Prevention Cloning Fluorescence Microscopy Immunohistochemistry Key Regulator Of Many Essential Pathways Mutagenesis Phosphatase Assay Quantitative Mass Spectrometry Western Blot Analysis

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英文摘要

The protein PP1 is important in many essential pathways in the cell. Disruptions in PP1 function can lead to the development of diseases such as cancer and diabetes. Our project involves determining which proteins PP1 is regulating. This research will aid

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