Overexpression of PARG deregulates epigenetic modifications in breast cancer

PARG 的过度表达会解除乳腺癌表观遗传修饰的调节

• 批准号: 252432
• 负责人: Lovato Amanda
• 金额: $ 1.27万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-02-01 至 2013-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=252432&lang=en
• 关键词: Cancer; Chromatin Immunoprecipiation; Ctcf; Epigenetics; P16; Parg; Parp

Cancer is characterized by abnormal, uncontrolled division of cells. This is the result of a change analogous to 'stepping on the accelerator', or alternatively, losing the 'brake' controlling growth. Recent evidence has shown that one of the initiating s

癌症的特点是细胞分裂不正常，不受控制。这是一种类似于“踩油门”的变化的结果，或者说，失去了控制增长的“刹车”。最近的证据表明，发起人之一S