Genetic Regulation of Myogenesis

肌生成的遗传调控

• 批准号: 253015
• 负责人: Rudnicki Michael A
• 金额: $ 73.74万
• 依托单位: Ottawa Hospital Research Institute
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-03-01 至 2017-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=253015&lang=en
• 关键词: Bioinformatics; Chromatin Immunoprecipitation Sequencing (Chip-Seq); Differentiation; Epigenetics; Massively Parallel Dna Sequencing; Mrf4; Muscular Dystrophy; Myf5; Myod; Myogenesis; Myogenin; Pax3; Pax7; Progenitors; Stem Cells; Transcriptional Networks

In adult skeletal muscle, satellite cells are specialized cells whose job is to replenish muscle tissue lost through damage or disease. At the molecular level, the behavior of the satellite cells and their descendants in carrying out this role is regulat

在成人骨骼肌中，卫星细胞是专门的细胞，其工作是补充因损伤或疾病而丢失的肌肉组织。 在分子水平上，卫星细胞及其后代在执行这一角色时的行为是受调节的。