Identification of miRNAs and their Specific Gene Targets that are Critical for Prostate Cancer Metastases

鉴定对前列腺癌转移至关重要的 miRNA 及其特定基因靶标

• 批准号: 252653
• 负责人: Wang Yuzhuo
• 金额: $ 56.46万
• 依托单位: BC Cancer, part of PHSA (Vancouver)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-03-01 至 2016-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=252653&lang=en
• 关键词: Metastasis; Mirna; Oncolytic Virus; Prostate Cancer; Therapy; Xenograft

It is likely that specific miRNAs, a class of non-protein-encoding, small RNAs may be potential therapeutic targets for controlling metastases. Accordingly, the hypotheses to be tested in this proposal are that: (i) metastasis-associated miRNAs can be ide

特异性的miRNAs（一类非蛋白质编码的小RNA）可能是控制转移的潜在治疗靶点。因此，本研究的假设是：（i）转移相关的miRNAs可以被认为是肿瘤转移相关的miRNAs。