Leukocyte Ig-Like Receptor-B1 Regulation and Function

白细胞 Ig 样受体-B1 调节和功能

• 批准号: 252155
• 负责人: Burshtyn Deborah N
• 金额: $ 41.26万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-03-01 至 2017-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=252155&lang=en
• 关键词: Gene Regulation; Inhibitory Motifs; Innate Immunity; Natural Killer Cells; Polymorphism; Receptor Signaling

The goal of this study is to fully understand how cells of the immune system integrate signals to respond only when appropriate. Failure to tightly regulate this process results in needless damage to tissues and can lead to full-blown autoimmunity where t

这项研究的目的是充分了解免疫系统的细胞如何整合信号，只有在适当的时候才做出反应。如果不能严格调节这一过程，就会导致对组织不必要的损伤，并可能导致全面的自身免疫，