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The epigenetic impact of deregulated poly(ADP)ribosylation in breast cancer.

The epigenetic impact of deregulated poly(ADP)ribosylation in breast cancer.
乳腺癌中多聚(ADP)核糖基化失调的表观遗传影响。
批准号:
252898
负责人:
Witcher Michael
金额:
$50.7万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2012
资助国家:
加拿大
项目状态:
已结题
起止时间:
2012-03-01 至 2017-03-01

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中文摘要
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英文摘要
Cancer is characterized by abnormal, uncontrolled division of cells. Recent evidence has shown that one of the initiating steps leading to this type of malignant growth in breast cancer is the silencing (switching off) of tumor suppressor genes. These gen
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Targeting changes to chromatin architecture that promote breast cancer metastasis.
Targeting changes to chromatin architecture that promote breast cancer metastasis.
Targeting changes to chromatin architecture that promote breast cancer metastasis.
Oncogenic activity of poly (ADP-ribose) polymerase.
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