Androgen Receptor Activation by Glucocorticoid Metabolite: a Novel Player in the Physiopathology of Respiratory Distress Syndrome in Neonates

糖皮质激素代谢物激活雄激素受体：新生儿呼吸窘迫综合征病理生理学的新参与者

• 批准号: 252493
• 负责人: Tremblay Yves
• 金额: $ 34.5万
• 依托单位: Centre hospitalier de l'Universit Laval (Qubec)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-03-01 至 2017-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=252493&lang=en
• 关键词: Bpd; Disease: Problem Link To Premature Birth And; Expertise: Lung Biology And Physiology; General Endocrinology And Molecular Biology; Lung Development (Impaired Alveolar And Capillary Growth); Microarns; Placental Physiology; Primary Cultures Of Endothe

Androgens are considered as male sex hormones and they are normally produced by testis. On the other hand, we have demonstrated that they are produced in the developing lung of both sexes where they should play a physiological role. Consequently, how can

雄激素被认为是男性性激素，通常由睾丸产生。另一方面，我们已经证明它们是在两性发育中的肺部产生的，它们应该在其中发挥生理作用。因此，怎样才能