MicroRNAs and gene regulation on vascular remodeling in hypertension from mice to humans

MicroRNA 和基因调控对小鼠和人类高血压血管重塑的影响

• 批准号: 252283
• 负责人: Schiffrin Ernesto L
• 金额: $ 42.52万
• 依托单位: CIUSSS de Centre-Ouest-de-l'Ile-de-Montral-Jewish General
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-03-01 至 2017-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=252283&lang=en
• 关键词: Angiotensin/Aldosterone; Experimental And Human Essential Hypertension; Gene Expression; Messenger Rna; Metabolic Syndrome; Microrna; Vascular Remodeling

High blood pressure is one of the most important causes of disease and death in humans. It leads to heart attacks, strokes and failure of the kidneys. In large measure this is because it causes injury to blood vessels. Genes regulate the degree to which e

高血压是导致人类疾病和死亡的最重要原因之一。它会导致心脏病发作、中风和肾脏衰竭。这在很大程度上是因为它会对血管造成伤害。基因在多大程度上调节着