Statistical mechanics with applications in micro- and nano-fluidics and in biological physics

统计力学在微米和纳米流体以及生物物理学中的应用

• 批准号: 46434-2007
• 负责人: Slater, Gary
• 金额: $ 4.92万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=513537
• 关键词: Statistical; mechanics; applications; micro; nano

Over the last decade, we have witnessed a remarkable convergence of the experimental and computational sciences. On the one hand, experimentalists can now visualize, manipulate and study single molecules such as DNA or proteins or build nanoscopic systems made of a very small number of molecules. One even has nanofluidic systems where nano-channels are filled with liquids. On the other hand, theoreticians now possess the theoretical and computational tools to study the very same systems, molecule by molecule. This convergence opens incredible possibilities in a number of disciplines, including analytical biochemistry and separation sciences. In this proposal, we propose to make significant contribution to various problems related to the dynamics of polymeric molecules (such as DNA) and nanofluidics:

在过去的十年里，我们见证了实验科学和计算科学的惊人融合。一方面，实验学家现在可以可视化，操纵和研究单个分子，如DNA或蛋白质，或构建由非常少量的分子组成的纳米级系统。甚至有纳米流体系统，其中纳米通道充满液体。另一方面，理论家现在拥有理论和计算工具，可以逐个分子地研究相同的系统。这种融合在许多学科中开辟了令人难以置信的可能性，包括分析生物化学和分离科学。在这项提案中，我们提出对与聚合物分子（如DNA）和纳米流体动力学相关的各种问题做出重大贡献：