Dissecting the Molecular Mechanisms of the Alternative Nuclear Export and Endoplasmic Reticulum Targeting of Secretory mRNAs.

剖析分泌 mRNA 的替代核输出和内质网靶向的分子机制。

• 批准号: 268978
• 负责人: Palazzo Alexander F
• 金额: $ 21.86万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Salary Programs
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-09-01 至 2017-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=268978&lang=en
• 关键词: Endoplasmic Reticulum; Mrna Localization; Nuclear Transport; Post-Transcriptional Regulation Of Gene Expression; Secretion

During gene activation, segments of DNA are transcribed into messenger RNA (mRNA) in the nucleus. These RNA transcripts are processed, exported into the cytoplasm and then delivered to particular regions, depending on elements that are found within each m

在基因激活过程中，DNA 片段在细胞核中转录成信使 RNA (mRNA)。这些 RNA 转录本经过处理、输出到细胞质中，然后递送到特定区域，具体取决于每个 m 中发现的元素。