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The role of FOXP3 and IL-1-family cytokines in regulating CD4+ T cell subsets in healthy humans, and in patients with chronic skin inflammation.

The role of FOXP3 and IL-1-family cytokines in regulating CD4+ T cell subsets in healthy humans, and in patients with chronic skin inflammation.
FOXP3 和 IL-1 家族细胞因子在调节健康人和慢性皮肤炎症患者 CD4 T 细胞亚群中的作用。
批准号：
266063
负责人：
Levings Megan K
金额：
$40.5万
依托单位：
BC Children's Hospital Research Institute
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-09-01 至 2016-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=266063&lang=en
关键词：
Autoimmunity Fibroblasts Graft Versus Host Disease Inflammasome Interleukin 1 Skin Inflammation Systemic Sclerosis T Helper Cells T Regulatory Cells Transplantation

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中文摘要
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英文摘要
The immune system is designed to recognize the difference between harmful and non-harmful foreign proteins, and to not react against proteins that normally exist in an individual. Unfortunately, when the processes controlling these functions breakdown dis
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Use of CAR Tregs to induce transplantation tolerance
Allogeneic regulatory T cell therapy to prevent chronic graft versus host disease
Allogeneic thymus-derived Tregs to prevent chronic inflammation in transplantation.
Canada Research Chairs - Tier 1
  • 批准号：
    441796
  • 项目类别：
  • 资助金额：
    $101.99万
  • 财政年份：
    2020
  • 负责人：
    Levings Megan K
  • 依托单位：
    University of British Columbia
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