Two-Photon Chemistry of Small Organic Chromophores

小有机发色团的双光子化学

• 批准号: 227855-2013
• 负责人: Schepp, Norman
• 金额: $ 2.48万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=524131
• 关键词: Two; Photon; Chemistry; Small; Organic

Normally, a molecule can be induced to go from its normal ground state to an excited state by absorbing light (or a photon) with energy that matches the difference in energy between those two states. However, as predicted by Nobel laureate Maria Goeppert Mayer in the 1930's, the change from ground state to excited state can sometimes (depending on the properties of the molecule) be induced using two photons with each photon having about half the needed energy in a process called two-photon absorption. There is intense interest in this phenomena, since two-photon absorption (2PA) has several advantages over the more conventional one-photon absorption (1PA): the lower energy needed for 2PA is more compatible with photochemistry in biological systems due to the higher penetration abilities, and requirement for two-photons provides a much greater ability to irradiate microscopic areas, thus increasing the accuracy of irradiation. These advantages have led to a wide range of applications of two-photon chemistry in diverse areas ranging from health related fields (photodynamic therapy) to high tech fields (3D data storage).

通常，分子可以通过吸收具有与这两种状态之间的能量差相匹配的能量的光（或光子）而被诱导从其正常基态进入激发态。 然而，正如诺贝尔奖获得者玛丽亚·戈佩特·迈耶（Maria Goeppert Mayer）在20世纪30年代所预测的那样，从基态到激发态的变化有时可以（取决于分子的性质）使用两个光子来诱导，每个光子在称为双光子吸收的过程中具有大约一半的所需能量。由于双光子吸收（2PA）比传统的单光子吸收（1PA）具有几个优点，因此对这种现象有强烈的兴趣：由于更高的穿透能力，2PA所需的能量更低，与生物系统中的光化学更相容，并且对双光子的要求提供了更大的照射微观区域的能力，从而提高了照射的准确性。 这些优点导致了双光子化学在从健康相关领域（光动力疗法）到高科技领域（3D数据存储）的各种领域中的广泛应用。