Exploring B cells as key cellular players in controlling HIV propagation within mucosal tissues

探索 B 细胞作为控制粘膜组织内 HIV 传播的关键细胞角色

• 批准号: 270582
• 负责人: Li Conglei
• 金额: $ 9.83万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2012
• 资助国家: 加拿大
• 起止时间: 2012-10-01 至 2015-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=270582&lang=en
• 关键词: B Lymphocytes; Hiv; Iga; Mucosal Tissues; Tnf-Inos-Producing Plasma Cells

HIV infection is a major health problem worldwide and development of novel vaccines strategies is imperative to halt transmission. Since the virus invades mucosal tissues, vaccines that specifically prime white blood cells within mucosal tissues is a reas

艾滋病毒感染是世界范围内的一个主要健康问题，开发新的疫苗战略势在必行，以阻止传播。由于病毒侵袭粘膜组织，因此疫苗可以在粘膜组织中特异性激活白细胞。