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Conformation specific targeting of misfolded superoxide dismutase 1 as an immunotherapeutic strategy for Amyotrophic Lateral Sclerosis.

Conformation specific targeting of misfolded superoxide dismutase 1 as an immunotherapeutic strategy for Amyotrophic Lateral Sclerosis.
错误折叠的超氧化物歧化酶 1 的构象特异性靶向作为肌萎缩侧索硬化症的免疫治疗策略。
批准号：
277273
负责人：
Marciniuk Kristen
金额：
$3.82万
依托单位：
University of Saskatchewan
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2012
资助国家：
加拿大
项目状态：
已结题
起止时间：
2012-10-01 至 2015-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=277273&lang=en
关键词：
Amyotrophic Lateral Sclerosis Conformation Specific Antibodies Immunotherapy Peptide Epitope Optimization Protein Misfolding Self-Epitope Sod1 Vaccine Design

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中文摘要
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英文摘要
Amyotrophic Lateral Sclerosis (ALS), also referred to as "Lou-Gehrig's Disease", is the most common motor neuron disease. ALS is characterized by a rapidly progressive degeneration of motor neurons, leading to a loss of muscle function, which often resul
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Specific Targeting of Monomeric SOD1 as a Potential Immunotherapeutic Strategy for ALS.
  • 批准号：
    225007
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $1.27万
  • 财政年份：
    2011
  • 负责人：
    Marciniuk Kristen
  • 依托单位：
    University of Saskatchewan
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