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The biophysics of cancer model systems: combined mathematical and experimental approaches for image analyses and interpretations

The biophysics of cancer model systems: combined mathematical and experimental approaches for image analyses and interpretations
癌症模型系统的生物物理学:结合数学和实验方法进行图像分析和解释
批准号:
341981-2013
负责人:
Wong, Eugene
金额:
$1.97万
依托单位国家:
加拿大
项目类别:
Discovery Grants Program - Individual
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-01-01 至 2014-12-31

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中文摘要
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英文摘要
We have been acquiring data in the form of images from dividing cancer cells suspended in 3D in cell cultures, as well as modern imaging of cancer growth in mice and rats, capturing their time evolution with and without radiation effects. We propose to augment the conventional analysis of these serial images, from basic change in tumour volume or tumour blood supply, to the inclusion of mathematical biophysical modeling of tumour growth and responses to treatment between the imaging time points. We will create a framework for the interpretation of experiments, which will enhance our understanding, for hypothesis generation, and facilitating design of new experiments.
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