Characterization of the mechanisms of AmpC beta-lactamase mediated antibiotic resistance in Pseudomonas aerugionsa

AmpC β-内酰胺酶介导的铜绿假单胞菌抗生素耐药性机制的表征

• 批准号: 281104
• 负责人: Lamers Ryan P
• 金额: $ 6.56万
• 依托单位: McMaster University
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-02-01 至 2015-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=281104&lang=en
• 关键词: Ampc Beta-Lactamase; Anhydromuropeptides; Antibiotic Resistance; Beta-Lactam Resistance; Environmental Pathogens; Lytic Transglycosylases; Penicillin-Binding Proteins; Peptidoglycan Metabolism; Pseudomonas Aeruginosa; Two Component System

Pseudomonas aeruginosa is a prevalent environmental pathogen that is a leading cause of hospital-acquired infection in immunocompromised, burn, and cystic fibrosis patients. Treatment of P. aeruginosa is particularly challenging because of its resistance

铜绿假单胞菌是一种普遍存在的环境病原体，是免疫功能低下、烧伤和囊性纤维化患者医院获得性感染的主要原因。铜绿假单胞菌的治疗尤其具有挑战性，因为它具有耐药性