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Systematic identification of dynamic epigenetic modifications in DNA damage repair for novel cancer therapy

Systematic identification of dynamic epigenetic modifications in DNA damage repair for novel cancer therapy
系统鉴定新型癌症疗法 DNA 损伤修复中的动态表观遗传修饰
批准号:
284732
负责人:
Li Shun-Cheng S
金额:
$16.39万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-03-01 至 2016-03-01

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中文摘要
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英文摘要
Epigenetics refers mainly to the study of DNA and histone modifications and their role in regulating the gene transcriptional program in cells. Aberrant epigenetic changes have been associated with a plethora of human diseases, including cancer. Histones
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Novel anticancer immunotherapy targeting the molecular mechanisms of T cell suppression by immune checkpoints
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    389208
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  • 资助金额:
    $69.66万
  • 财政年份:
    2018
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    Li Shun-Cheng S
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Canada Research Chair - Tier 1
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    378552
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    2017
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Characterization of a new histone mark in stem cell differentiation
  • 批准号:
    345296
  • 项目类别:
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  • 资助金额:
    $38.71万
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Characterizing the LeSH/LUSH superfamily of bacterial effector proteins in the pathogenesis of Legionnaires' disease
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    291198
  • 项目类别:
    Operating Grants
  • 资助金额:
    $45.01万
  • 财政年份:
    2013
  • 负责人:
    Li Shun-Cheng S
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