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Characterizing the molecular basis of ligand-biased signaling at beta-adrenergic G protein-coupled receptors

Characterizing the molecular basis of ligand-biased signaling at beta-adrenergic G protein-coupled receptors
表征 β-肾上腺素能 G 蛋白偶联受体配体偏向信号传导的分子基础
批准号:
184604
负责人:
Stallaert Wayne
金额:
$10.93万
依托单位:
依托单位国家:
加拿大
项目类别:
Studentship Programs
财政年份:
2008
资助国家:
加拿大
项目状态:
已结题
起止时间:
2008-11-01 至 2011-11-01

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英文摘要
G protein-coupled receptors (GPCRs) represent the largest class of cell-surface receptors and are the target of nearly 40% of prescription drugs, including treatments for hypertension, migraine and heart failure. Drugs targeting these receptors were tradi
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