Mechnisms of ventilator-induced lung injury and remodeling

呼吸机引起的肺损伤和重塑的机制

• 批准号: 284906
• 负责人: Slutsky Arthur S
• 金额: $ 16.39万
• 依托单位: Unity Health Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-03-01 至 2016-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=284906&lang=en
• 关键词: Epithelial Cell; Inflammation; Lung Injury; Mechanical Ventilation; Neutrophils

Patients who develop a disease known as Acute Respiratory Distress Syndrome (ARDS) have a very high mortality. Mortality is particularly high in the subset of patients with ARDS who develop fibrosis (scarring) in their lungs while they are on a breathing

患有急性呼吸窘迫综合征（ARDS）的患者死亡率非常高。在呼吸困难时肺纤维化（瘢痕形成）的ARDS患者中，死亡率特别高。