Design, Synthesis and Evaluation of Prodigiosin Analogues as Chemotherapeutic Agents

灵菌红类似物化疗药物的设计、合成及评价

• 批准号: 287029
• 负责人: Thompson Alison
• 金额: $ 12.6万
• 依托单位: Dalhousie University (Nova Scotia)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-03-01 至 2016-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=287029&lang=en
• 关键词: Chloride Transport; Collaborative And Interactive Evaluation; Drug Delivery; Folate Receptor Alpha; In Vitro Screening; Intracellular Ph; Medicinal Chemistry; Mouse Xenograft Models; Natural Product-Driven; Zebrafish Models

We are developing new drugs for breast cancer based on a naturally occurring molecule called prodigiosin found in bacteria in our homes and workplaces. Extracts containing prodigiosin were used in the USA from 1893 to 1963 to treat various cancers. Howeve

我们正在开发一种治疗乳腺癌的新药，这种新药是基于一种天然存在的分子，这种分子被称为prodigiosin，它存在于我们家里和工作场所的细菌中。从1893年到1963年，美国用含有神童红素的提取物来治疗各种癌症。但仍