Selective Translation of HIV-1 mRNAs: Mechanism and Effect on Host Innate Immune Responses
Selective Translation of HIV-1 mRNAs: Mechanism and Effect on Host Innate Immune Responses
批准号:
281409
负责人:
Cochrane Alan W
金额:
$52.57万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-03-01 至 2018-03-01
中文摘要
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英文摘要
Upon entry into a cell, viruses have two objectives; to maximize the production of progeny virions while minimizing the activation of innate immune sensors that will limit virus replication. Recent work by our group has demonstrated that HIV-1 inhibits ho
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海外基金