The role of transcription factors Nur77 and retinoid X receptor (RXR) in the effect of antipsychotic drugs

转录因子Nur77和类维生素A X受体（RXR）在抗精神病药物作用中的作用

• 批准号: 280025
• 负责人: Levesque Daniel
• 金额: $ 36.22万
• 依托单位: Universit de Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-03-01 至 2018-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=280025&lang=en
• 关键词: Antipsychotic Drugs; Dopamine D2 Receptors; Drug-Induced Biomarker; Dyskinesia; Gene Expression; Neuropharmacology; Nuclear Receptors; Retinoids; Single Nucleotide Polymorphism; Transcription Factors

Dopamine is an important neurotransmitter. It modulates various activity including, locomotion, motivated behaviors and neuroendocrine processes. Antipsychotic drugs are used to alleviate schizophrenia symptoms and share the common property to interact wi

多巴胺是一种重要的神经递质。它调节各种活动，包括运动，动机行为和神经内分泌过程。抗精神病药物用于缓解精神分裂症症状，并具有共同的特性，即与精神分裂症药物相互作用。