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Role of ILK/Rictor complex in the TGF-b and Hippo signaling pathway mediated EMT, cancer stem cell function and tumor progression

Role of ILK/Rictor complex in the TGF-b and Hippo signaling pathway mediated EMT, cancer stem cell function and tumor progression
ILK/Rictor 复合物在 TGF-b 和 Hippo 信号通路介导的 EMT、癌症干细胞功能和肿瘤进展中的作用
批准号：
285898
负责人：
Dedhar Shoukat R
金额：
$7.29万
依托单位：
B.C. Cancer Research Centre (Vancouver)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-03-01 至 2014-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=285898&lang=en
关键词：
14:3:3 Protein Cancer Stem Cells Epithelial-Mesenchymal Transition Hippo Pathway Integrin Linked Kinase Metastasis Rictor Targeted Cancer Therapeutics Tgf-Beta Wnt Signaling

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We have been investigating the molecular basis of a fundamental process called "Epithelial to Mesenchymal Transition" ( EMT), which converts normal and cancer cells into highly migratory and invasive cells, leading to the spread of tumor cells from the pr
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Investigation of Neutrophil Extracellular Trap DNA ( NET-DNA) induced signaling in the progression of Pancreatic Ductal Adenocarcinoma
The Role of Microbiota and Immune Microenvironment in Breast Cancer Metastasis
  • 批准号：
    453393
  • 项目类别：
    Operating Grants
  • 资助金额：
    $4.37万
  • 财政年份：
    2021
  • 负责人：
    Dedhar Shoukat R
  • 依托单位：
    BC Cancer, part of PHSA (Vancouver)
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