Role of ILK/Rictor complex in the TGF-b and Hippo signaling pathway mediated EMT, cancer stem cell function and tumor progression
ILK/Rictor 复合物在 TGF-b 和 Hippo 信号通路介导的 EMT、癌症干细胞功能和肿瘤进展中的作用
基本信息
- 批准号:285898
- 负责人:
- 金额:$ 7.29万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Operating Grants
- 财政年份:2013
- 资助国家:加拿大
- 起止时间:2013-03-01 至 2014-03-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
We have been investigating the molecular basis of a fundamental process called "Epithelial to Mesenchymal Transition" (
EMT), which converts normal and cancer cells into highly migratory and invasive cells, leading to the spread of tumor cells
from the pr
我们一直在研究称为“上皮到间质转化”的基本过程的分子基础(
EMT),将正常细胞和癌细胞转化为高度迁移和侵袭的细胞,导致肿瘤细胞扩散
从公关
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Dedhar Shoukat R其他文献
Dedhar Shoukat R的其他文献
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{{ truncateString('Dedhar Shoukat R', 18)}}的其他基金
Investigation of Neutrophil Extracellular Trap DNA ( NET-DNA) induced signaling in the progression of Pancreatic Ductal Adenocarcinoma
中性粒细胞胞外陷阱 DNA (NET-DNA) 诱导的胰腺导管腺癌进展中的信号传导研究
- 批准号:
468385 - 财政年份:2022
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
The Role of Microbiota and Immune Microenvironment in Breast Cancer Metastasis
微生物群和免疫微环境在乳腺癌转移中的作用
- 批准号:
453393 - 财政年份:2021
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
The Role of Tumor Microenvironment in Cancer Progression: Identification and Therapeutic Intervention of Novel Targets
肿瘤微环境在癌症进展中的作用:新靶标的识别和治疗干预
- 批准号:
312327 - 财政年份:2014
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
Development of therapeutic antibodies targeting carbonic anhydrase IX (CAIX)
开发针对碳酸酐酶 IX (CAIX) 的治疗性抗体
- 批准号:
291012 - 财政年份:2013
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
Role of Integrin-Linked Kinase in Mitotic Spindle dynamics and Centrosome clustering in cancer cells
整合素连接激酶在癌细胞有丝分裂纺锤体动力学和中心体聚集中的作用
- 批准号:
179794 - 财政年份:2009
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
Targeting Carbonic Anhydrase IX and Hypoxia for the diagnosis and treatment of aggresive breast cancers
靶向碳酸酐酶 IX 和缺氧用于诊断和治疗侵袭性乳腺癌
- 批准号:
189452 - 财政年份:2009
- 资助金额:
$ 7.29万 - 项目类别:
Operating Grants
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集成拉曼显微镜和水凝胶平台进行癌症干细胞的代谢分析
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Role of V-ATPase for Regulating Acidification and Survival in Cancer Stem Cells
V-ATP酶在调节癌症干细胞酸化和存活中的作用
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胶质瘤干细胞内源合成 TRAIL 及对 TRAIL 治疗的耐药性
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横纹肌肉瘤细胞状态、癌症干细胞和转移的致癌驱动因素
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10658091 - 财政年份:2023
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针对多形性胶质母细胞瘤癌症干细胞预后不良的代谢组学机制。
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阐明癌症干细胞中嗅觉受体的选择性表达机制和意义。
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阐明子宫内膜癌干细胞多样性和可塑性的分子机制并开发新型多方面疗法
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