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Control of Kidney Development by Sox4 and Sox11 Transcription Factors

Control of Kidney Development by Sox4 and Sox11 Transcription Factors
Sox4 和 Sox11 转录因子对肾脏发育的控制
批准号：
287005
负责人：
Hartwig Sunny
金额：
$10.93万
依托单位：
University of Prince Edward Island (Charlottetown)
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-03-01 至 2017-03-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=287005&lang=en
关键词：
Glomerular Disease Kidney Development Nephrogenesis Nephron Progenitor Survival And Self-Renewal Sox11 Sry-Related Hmg Box 4 (Sox4) Transcription Factor Signaling Wilms' Tumour Suppressor-1 (Wt1)

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英文摘要
The childhood kidney diseases Frasier Syndrome and Denys Drash Syndrome are associated with a poorer quality of life, the need for dialysis, and in severe cases, end-stage kidney failure requiring kidney replacement. Both of these diseases are linked to g
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