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Omega current underlies SCN5A mutations associated with complex cardiac arrhythmias and dilated cardiomyopathy.

Omega current underlies SCN5A mutations associated with complex cardiac arrhythmias and dilated cardiomyopathy.
Omega电流是与复杂心律失常和扩张型心肌病相关的SCN5A突变的基础。
批准号:
280299
负责人:
Chahine Mohamed
金额:
$38.98万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-03-01 至 2017-03-01

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中文摘要
翻译
扩张性心肌病是一种心脏疾病,表现为心腔扩大,是北美心力衰竭的最常见原因。 十多年来,SCN5A基因一直被认为与心脏电有关
英文摘要
Dilation related cardiomyopathies are cardiac diseases that manifest as an enlargement of cardiac chambers and are the most common cause of heart failure in North America. For over a decade, SCN5A gene has been associated exclusively to cardiac electrica
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会议论文
Mechanisms of heart rhythm disorders and therapeutic interventions in myotonic dystrophy type 1
  • 批准号:
    433302
  • 项目类别:
    Operating Grants
  • 资助金额:
    $77.47万
  • 财政年份:
    2020
  • 负责人:
    Chahine Mohamed
  • 依托单位:
Investigating the role of gating pore current in cardiac arrhythmias associated with dilated cardiomyopathy
  • 批准号:
    357922
  • 项目类别:
    Operating Grants
  • 资助金额:
    $75.24万
  • 财政年份:
    2016
  • 负责人:
    Chahine Mohamed
  • 依托单位:
Investigating the internal and the external pore of Nav1.5 Voltage-gated sodium channel
海外基金