Metabolic fuel selection: Exercise and cold exposure

代谢燃料选择：运动和寒冷暴露

• 批准号: 105639-2012
• 负责人: Weber, JeanMichel
• 金额: $ 3.42万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=545186
• 关键词: Metabolic; fuel; selection; Exercise; cold

This research deals with the ability of animals to survive in the cold and to perform long-distance migrations. The first project investigates how fish cope with changes in temperature and environmental contaminants like PCBs. Cold-blooded animals must be able to modify cell membranes to ensure the maintenance of normal metabolism as their body temperature fluctuates. Because many PCBs accumulate within membranes, it is particularly important to know whether these toxins interfere with the life-saving changes in membranes taking place during acclimation to different temperatures.

这项研究涉及动物在寒冷中生存和进行长距离迁徙的能力。第一个项目研究鱼类如何科普温度和环境污染物（如PCB）的变化。 冷血动物必须能够改变细胞膜，以确保在体温波动时维持正常的新陈代谢。由于许多多氯联苯在细胞膜内积累，因此了解这些毒素是否会干扰细胞膜在适应不同温度期间发生的救生变化尤为重要。