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The Canadian HIV Cure Enterprise (CanCURE)

The Canadian HIV Cure Enterprise (CanCURE)
加拿大艾滋病治疗企业 (CanCURE)
批准号：
288007
负责人：
Cohen Eric A
金额：
$624.26万
依托单位：
Institut de recherches cliniques de Montral
依托单位国家：
加拿大
项目类别：
Operating Grants
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-06-01 至 2018-06-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=288007&lang=en
关键词：
Cd4+ T Lymphocytes And Myeloid Cells Hiv Cure Hiv Eradication Hiv Latency Hiv Persistence Human Trials Humanized Blt Mice Model Immune-Based Therapies Non Human Primate Model Oncolytic Viruses

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中文摘要
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英文摘要
Despite the success of antiretroviral therapy (ART) in decreasing mortality for HIV-infected patients, ART has not cured HIV/AIDS. The failure to eradicate HIV infection during ART stems from the virus' ability to persist in the body, in multiple cell typ
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Canadian HIV Cure Enterprise 2.0: Targeting the interplay between myeloid cells and CD4+ T-cells for HIV cure
Targeting of host antiviral and immune-modulatory factors by HIV-1 Vpu: Implications for viral pathogenesis and therapy
Plasmacytoid dendritic cells in HIV infection
Examining the role of plasmacytoid dendritic cells in the control of HIV infection using humanized mice
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