Cuticular wax biosynthesis, regulation and intracellular trafficking

角质层蜡生物合成、调节和细胞内运输

• 批准号: 194172-2013
• 负责人: Kunst, Ljerka
• 金额: $ 4.15万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=546069
• 关键词: Cuticular; wax; biosynthesis; regulation; intracellular

Cuticular wax covers aerial surfaces of land plants and serves as a protective barrier against water loss, UV-light, pathogens and insects. Major wax components are derived from saturated very long chain fatty acids (VLCFAs; >C20 in length) via two biosynthetic pathways: an alcohol-forming and an alkane-forming pathway. Similar cuticular wax compositions found in Arabidopsis and other species suggest that wax biosynthesis is highly conserved in plants. However, our knowledge in several key areas remains limited, including how wax precursors are formed, how wax production is regulated, and how waxes are transported in epidermal cells en route to the plant surface.

表皮蜡覆盖陆地植物的气生表面，并作为防止水分流失、紫外线、病原体和昆虫的保护屏障。主要的蜡组分通过两种生物合成途径衍生自饱和极长链脂肪酸（VLCFA;长度>C20）：醇形成途径和烷烃形成途径。在拟南芥和其他物种中发现的类似表皮蜡组成表明蜡的生物合成在植物中是高度保守的。然而，我们在几个关键领域的知识仍然有限，包括蜡前体是如何形成的，蜡的产生是如何调节的，以及蜡是如何在表皮细胞中运输到植物表面的。