Functional characterization of pilus and secretion system biogenesis in Vibrio parahaemolyticus

副溶血弧菌菌毛和分泌系统生物发生的功能特征

• 批准号: 342111-2013
• 负责人: Thomas, Nikhil
• 金额: $ 2.19万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=549594
• 关键词: Functional; characterization; pilus; secretion; system

Vibrio parahaemolyticus (Vp) is a halophilic bacterium commonly found in marine estuarine environments. Vp attaches to a variety of shellfish, especially oysters and crabs, and as a result, Vp contaminated shellfish poses a significant threat to human health when poorly cooked or raw seafood is consumed. For this reason, advanced knowledge of how Vp adheres to shellfish and how Vp secretes toxins during infection is required.

副溶血性弧菌（Vp）是一种常见于海洋河口环境的嗜盐细菌。Vp附着在多种贝类上，特别是牡蛎和螃蟹，因此，当食用未煮熟或生的海鲜时，Vp污染的贝类对人类健康构成重大威胁。因此，需要了解Vp如何附着在贝类上以及Vp在感染过程中如何分泌毒素。