Large scale analysis of synthetic cytotoxic interactions with DNA damaging therapeutic agents
Large scale analysis of synthetic cytotoxic interactions with DNA damaging therapeutic agents
批准号:
293025
负责人:
Hieter Philip A
金额:
$48.53万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2013
资助国家:
加拿大
项目状态:
已结题
起止时间:
2013-09-01 至 2018-09-01
中文摘要
有效的癌症治疗是利用癌细胞和正常细胞之间的特定生物学差异。肿瘤细胞经常存在缺陷,从而降低DNA修复的效率。目前的许多抗癌疗法,如放射疗法,都利用了这些差异。
英文摘要
Effective cancer therapy exploits specific biological differences between cancer cells and normal cells. Tumour cells often have defects that reduce the efficiency of DNA repair. Many current anti-cancer therapies, such as radiation, exploit these diffe
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会议论文
Canadian "Rare Diseases: Models and Mechanisms" (RDMM) Network
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批准号:465679
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项目类别:Directed Grant
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资助金额:$182.13万
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财政年份:2022
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负责人:Hieter Philip A
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依托单位:
Canadian "Rare Diseases: Models and Mechanisms" (RDMM) Network
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批准号:386122
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项目类别:Operating Grants
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资助金额:$81.56万
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财政年份:2018
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负责人:Hieter Philip A
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依托单位:
Chromosome instability and synthetic lethality in yeast and cancer
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批准号:333514
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项目类别:Operating Grants
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资助金额:$184.04万
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财政年份:2015
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负责人:Hieter Philip A
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依托单位:
Canadian "Rare Diseases: Models & Mechanisms" Network (RDMM) Réseau Canadien "Maladies Rares: Modèles et Mécanismes" (MRMM)
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批准号:309096
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项目类别:Operating Grants
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资助金额:$152.99万
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财政年份:2014
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负责人:Hieter Philip A
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依托单位:
Determinants of Genome Stability
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批准号:201360
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项目类别:Operating Grants
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资助金额:$73.66万
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财政年份:2010
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负责人:Hieter Philip A
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依托单位: