Cell-adhesion mechanisms that control GABAergic synapse development

控制 GABA 突触发育的细胞粘附机制

• 批准号: 291506
• 负责人: Takahashi Hideto
• 金额: $ 51.58万
• 依托单位: Institut de recherches cliniques de Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-09-01 至 2018-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=291506&lang=en
• 关键词: Epilepsy; Excitation And Inhibition Balance; Gabaergic Synapse; Immunofluorescent Imaging; Intracranial Electroencephalogram (Eeg); Knockout Mouse; Neuron Culture; Neuronal Adhesion; Neuropsychiatric Disorder; Synapse Development

Normal brain function relies on a balance between excitation and inhibition of neurons. Disruption of this balance is involved in several neuropsychiatric disorders including autism, schizophrenia, and attention deficit hyperactive disorder as well as epi

正常的大脑功能有赖于神经元兴奋和抑制之间的平衡。这种平衡的破坏与几种神经精神疾病有关，包括自闭症、精神分裂症、注意力缺陷多动障碍以及外周精神障碍