Biased, Allosteric Regulation of Angiotensin II type 1 receptor Signalling and Trafficking

血管紧张素 II 1 型受体信号传导和运输的偏向变构调节

• 批准号: 291106
• 负责人: Laporte Stphane A
• 金额: $ 46.56万
• 依托单位: Research Institute of the McGill University Health Centre
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-09-01 至 2018-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=291106&lang=en
• 关键词: Allostery; Angiotesin Ii Type 1 Receptor; Arrestin; Biased Signalling; Cardiovascular Therapy; Drug Discovery; Gpcr; Trafficking

According to the World Health Organization, 30% of all deaths are attributable to cardiovascular diseases, and represent the second cause of death in Canada with more than 68,000 Canadians dying from such complications yearly. Despite advancements in prev

根据世界卫生组织的数据，30%的死亡可归因于心血管疾病，并且是加拿大的第二大死亡原因，每年有超过68，000名加拿大人死于此类并发症。尽管在前一阶段取得了进展，