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The role of PDZ proteins in the regulation of the signaling and trafficking of the corticotropin releasing factor 1 and serotonin 2A receptors

The role of PDZ proteins in the regulation of the signaling and trafficking of the corticotropin releasing factor 1 and serotonin 2A receptors
PDZ 蛋白在促肾上腺皮质激素释放因子 1 和血清素 2A 受体的信号传导和运输调节中的作用
批准号：
307749
负责人：
Hammad Maha M
金额：
$7.65万
依托单位：
University of Western Ontario
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2013
资助国家：
加拿大
项目状态：
已结题
起止时间：
2013-10-01 至 2016-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=307749&lang=en
关键词：
Anxiety Bioluminescence Resonance Energy Transfer (Bret) Confocal Microscopy Corticotropin Releasing Factor Receptors Depression Endocytosis G-Protein Coupled Receptors Molecular Signaling Pdz-Binding Proteins Serotonin Receptors

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Stress, anxiety and depression are co-morbid disorders that represent a major health concern in Canada, as 16% of adults will be affected by stress, anxiety and depression in their life-time, with women being twice as susceptible to the disease as men. T
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