Identifying new physiological biomarkers of Alzheimer's disease from functional and perfusion MRI

从功能性和灌注 MRI 中识别阿尔茨海默病的新生理生物标志物

• 批准号: 293745
• 负责人: MacIntosh Bradley J
• 金额: $ 7.29万
• 依托单位: Sunnybrook Research Institute (Toronto, Ontario)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-10-01 至 2015-10-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=293745&lang=en
• 关键词: Alzheimer'S Disease; Arterial Spin Labeling Perfusion; Cardiac Pulsatility; Mild Cognitive Impairment; Resting State Functional Magnetic Resonance Imaging; Small Vessel Disease

Alzheimer's disease (AD) is the most common type of dementia and is the result of accumulating beta-amyloid plaques and tau protein tangles, regional loss of brain tissue and a myriad of cognitive symptoms. Diagnostic magnetic resonance imaging (MRI) can

阿尔茨海默病(AD)是最常见的痴呆症类型，是β-淀粉样斑块和tau蛋白缠结积累、脑组织区域性丢失和无数认知症状的结果。诊断磁共振成像(MRI)可以