Investigating tropical enteropathy as a cause of oral rotavirus vaccine failure in the developing world

调查热带肠病是发展中国家口服轮状病毒疫苗失败的原因

• 批准号: 300341
• 负责人: Wagar Lisa E
• 金额: $ 10.93万
• 依托单位: Stanford University (California)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-11-01 至 2016-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=300341&lang=en
• 关键词: Gastrointestinal Disease; Oral Vaccine Failure; Pediatric Vaccination; Phosphoflow; Rotavirus; Time-Of-Flight Mass Cytometry; Tropical Enteropathy; Viral Immunology

One of the main causes of childhood death in developing nations is diarrheal disease, usually initiated by exposure to infectious agents such as rotavirus. There are two main oral vaccines available for rotavirus immunization. Although they are very effec

在发展中国家，儿童死亡的主要原因之一是腹泻病，通常是由接触轮状病毒等传染性病原体引起的。有两种主要的口服疫苗可用于轮状病毒免疫。虽然它们非常有效，