Sensory neuron silencing reverses allergic airway inflammation

感觉神经元沉默可逆转过敏性气道炎症

• 批准号: 301064
• 负责人: Talbot Sbastien
• 金额: $ 10.93万
• 依托单位: Boston Children's Hospital (Boston, MA)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-11-01 至 2016-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=301064&lang=en
• 关键词: Asthma; Chronic Neurogenic Inflammation; Flow Cytometry; Local Anesthetic; Neuro-Immunology; Neuropeptide; Qx-314; Rna-Seq; Sensory Neurons; Trpv1/Trpa1 Channel

Asthma is a chronic inflammatory disease of the airway characterized by reduced airflow and affects more than 300 million patients worldwide. Although bronchodilators and steroids control disease symptoms and can abort attacks, children with severe asthma

哮喘是一种以气流减少为特征的气道慢性炎症性疾病，影响着全世界3亿多患者。虽然支气管扩张剂和类固醇可以控制疾病症状，并可以中止发作，但严重哮喘儿童