Combinatorial Gene Therapy for the Treatment of Early- and Late-Stage Osteoarthritis
治疗早期和晚期骨关节炎的组合基因疗法
基本信息
- 批准号:301198
- 负责人:
- 金额:$ 10.93万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Fellowship Programs
- 财政年份:2013
- 资助国家:加拿大
- 起止时间:2013-11-01 至 2016-11-01
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Articular cartilage is the smooth, white connective tissue located at the ends of bones within synovial joints such as the knee. Osteoarthritis is a degenerative disease characterized by articular cartilage loss and joint inflammation that result in sever
关节软骨是光滑的,白色结缔组织,位于滑膜关节(如膝关节)内的骨末端。骨关节炎是一种退行性疾病,其特征是关节软骨丧失和关节炎症,
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Grol Matthew W其他文献
Grol Matthew W的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Grol Matthew W', 18)}}的其他基金
Implementation of EDI-D Principles and Open Communication Practices for Scientific Innovation and Dissemination - A New Canadian Connective Tissue Conference Workshop
实施 EDI-D 原则和科学创新和传播的开放式交流实践 - 加拿大新结缔组织会议研讨会
- 批准号:
487891 - 财政年份:2023
- 资助金额:
$ 10.93万 - 项目类别:
Miscellaneous Programs
Immunomodulatory Gene Therapy Strategies for Post-Traumatic and Metabolic Forms of Osteoarthritis
创伤后和代谢型骨关节炎的免疫调节基因治疗策略
- 批准号:
445209 - 财政年份:2021
- 资助金额:
$ 10.93万 - 项目类别:
Operating Grants
Nucleotide signaling in bone: The role of P2X7-induced microvesicle release in regulation of bone formation and resorption
骨中的核苷酸信号传导:P2X7 诱导的微泡释放在骨形成和吸收调节中的作用
- 批准号:
184463 - 财政年份:2008
- 资助金额:
$ 10.93万 - 项目类别:
Studentship Programs
相似海外基金
Mechanism of hyaluronan-degrading enzyme HYBID expression by chondrocytes and its regulation by microRNAs
软骨细胞表达透明质酸降解酶HYBID的机制及其microRNA的调控
- 批准号:
23K08613 - 财政年份:2023
- 资助金额:
$ 10.93万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Elucidation of the molecular mechanism of transdifferentiation from chondrocytes to osteoblasts by Runx2
Runx2阐明软骨细胞向成骨细胞转分化的分子机制
- 批准号:
23K09121 - 财政年份:2023
- 资助金额:
$ 10.93万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Intracellular proteostatic function of CCN2 in chondrocytes during endochondral ossification
软骨内骨化过程中软骨细胞CCN2的细胞内蛋白抑制功能
- 批准号:
23K09352 - 财政年份:2023
- 资助金额:
$ 10.93万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Autonomous RUNX2 suppression in genetically modified stem cell-derived chondrocytes as a disease modifying therapeutic for PTOA
转基因干细胞衍生软骨细胞中的自主 RUNX2 抑制作为 PTOA 的疾病修饰疗法
- 批准号:
10574780 - 财政年份:2023
- 资助金额:
$ 10.93万 - 项目类别:
Molecular mechanisms of control of ca2+ in chondrocytes in cartilage development and in the repair of articular cartilages
软骨发育和关节软骨修复过程中软骨细胞中 ca2 控制的分子机制
- 批准号:
23K08687 - 财政年份:2023
- 资助金额:
$ 10.93万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Understanding how secretory responses shape the downstream response of chondrocytes to inflammatory cytokine stimulation
了解分泌反应如何影响软骨细胞对炎症细胞因子刺激的下游反应
- 批准号:
2749889 - 财政年份:2022
- 资助金额:
$ 10.93万 - 项目类别:
Studentship
Transcriptional control of growth plate chondrocytes
生长板软骨细胞的转录控制
- 批准号:
10620128 - 财政年份:2022
- 资助金额:
$ 10.93万 - 项目类别:
CAREER: Integrin-Mediated Mechanotransduction of Articular Chondrocytes
职业:整合素介导的关节软骨细胞机械转导
- 批准号:
2144240 - 财政年份:2022
- 资助金额:
$ 10.93万 - 项目类别:
Standard Grant
Transcriptional control of growth plate chondrocytes
生长板软骨细胞的转录控制
- 批准号:
10342008 - 财政年份:2022
- 资助金额:
$ 10.93万 - 项目类别:
Dysfunctional mechanotransduction in senescent chondrocytes as a link between aging and osteoarthritis
衰老软骨细胞中功能失调的机械转导是衰老与骨关节炎之间的联系
- 批准号:
10313205 - 财政年份:2021
- 资助金额:
$ 10.93万 - 项目类别: