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Microfabricated microporous membranes prolong the functional lifetime of a closed-loop insulin delivery implant in a type I diabetic rat model by passively modulating the host immune response

Microfabricated microporous membranes prolong the functional lifetime of a closed-loop insulin delivery implant in a type I diabetic rat model by passively modulating the host immune response
微加工微孔膜通过被动调节宿主免疫反应，延长 I 型糖尿病大鼠模型中闭环胰岛素输送植入物的功能寿命
批准号：
315391
负责人：
Li Jason
金额：
$0.11万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
财政年份：
2014
资助国家：
加拿大
项目状态：
已结题
起止时间：
2014-09-01 至 2015-09-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=315391&lang=en
关键词：
Closed Loop Insulin Delivery Implant Biocompatability Implantable Device Insulin Delivery Responsive Polymer Type I Diabetes

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英文摘要
Objective: Closed-loop insulin delivery systems offer diabetic patients improved glycemic control, compliance and quality of life, however long-term efficacy has yet to be demonstrated due to poor device biocompatibility. Sustained administration of anti-
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