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Clonal evolution and acquired drug resistance in breast cancer patient xenografts profiled at single cell resolution

Clonal evolution and acquired drug resistance in breast cancer patient xenografts profiled at single cell resolution
以单细胞分辨率分析乳腺癌患者异种移植物的克隆进化和获得性耐药性
批准号：
327795
负责人：
Steif Adi
金额：
$7.65万
依托单位：
BC Cancer, part of PHSA (Vancouver)
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2014
资助国家：
加拿大
项目状态：
已结题
起止时间：
2014-10-01 至 2017-10-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=327795&lang=en
关键词：
Breast Cancer Clonal Evolution Computational Models Drug Resistance Single Cell Sequencing Tumour Heterogeneity

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英文摘要
Cancer is the leading cause of death in Canada and worldwide. Cancer tumours generally arise from a single cell which has acquired genetic mutations leading to uncontrolled cell division. As cancer cells divide, they acquire additional mutations which are
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    477688
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  • 财政年份：
    2022
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Clonal evolution and acquired drug resistance in breast cancer patient xenografts profiled at single cell resolution
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    318276
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $10.93万
  • 财政年份：
    2014
  • 负责人：
    Steif Adi
  • 依托单位：
    University of British Columbia
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