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Cellular and functional analysis of H3K9me1 reader proteins and the H3K9me1 mark

Cellular and functional analysis of H3K9me1 reader proteins and the H3K9me1 mark
H3K9me1 阅读器蛋白和 H3K9me1 标记的细胞和功能分析
批准号:
318379
负责人:
Daze Kevin D
金额:
$10.93万
依托单位国家:
加拿大
项目类别:
Fellowship Programs
财政年份:
2014
资助国家:
加拿大
项目状态:
已结题
起止时间:
2014-11-01 至 2017-11-01
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中文摘要
翻译
异染色质是致密排列的DNA,它在转录上沉默,不再表达。异染色质的维持和形成在细胞身份中非常重要,在许多疾病中经常被错误调节。翻译后modifica
英文摘要
Heterochromatin is densely packed DNA that is transcriptionally silenced and no longer expressed. The maintenance and formation of heterochromatin is immensely important in cell identity and often misregulated in many diseases. Post-translational modifica
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Chemical probes and inhibitors of epigenetic pathways reliant on histone lysine methylation.
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