Role of Par3 in the Homeostatic Maintenance of Mammary Epithelial Cells.

Par3 在乳腺上皮细胞稳态维持中的作用。

• 批准号: 319254
• 负责人: Ahmed Syed M
• 金额: $ 10.93万
• 依托单位: Vanderbilt University (Tennessee)
• 依托单位国家: 加拿大
• 项目类别: Fellowship Programs
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-11-01 至 2017-11-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=319254&lang=en
• 关键词: Apoptosis; Cancer; Cell Polarity; Epithelial Cells; Exocyst; Par3; Signalling

Most breast cancers arise from epithelial cells that form the branched ducts of the mammary gland. Epithelial cells are organized in a distinct fashion where all the cells in the epithelial sheet are polarized to form a top and a bottom. Based on evidence

大多数乳腺癌是由形成乳腺分支导管的上皮细胞引起的。上皮细胞以一种截然不同的方式组织起来，上皮片中的所有细胞都被极化，形成顶部和底部。基于证据