Identifying DNA Methylation Mediators of Field Defect in Colorectal Cancer using Whole Methylome Analysis

使用全甲基化分析鉴定结直肠癌场缺陷的 DNA 甲基化介体

• 批准号: 331599
• 负责人: Yap Eva Shyong Quin
• 金额: $ 1.27万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-12-01 至 2015-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=331599&lang=en
• 关键词: Bioinformatics; Cancer Detection And Risk Assessment; Colorectal Cancer; Dna Methylation; Epigenomics; Field Defect

Colorectal cancer (CRC) initiation and progression are associated with the accumulation of genetic and epigenetic alterations. Epigenetic mechanisms are processes that can alter gene expression without changing the primary sequence of DNA. The best-charac

结直肠癌（CRC）的发生和进展与遗传和表观遗传改变的积累有关。表观遗传机制是可以改变基因表达而不改变DNA一级序列的过程。最好的charac