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Characterisation of a Small Non-Competitive Peptide Inhibitor of IL-1RI in Preterm Labor

Characterisation of a Small Non-Competitive Peptide Inhibitor of IL-1RI in Preterm Labor
IL-1RI 小非竞争性肽抑制剂在早产中的表征
批准号：
331286
负责人：
Nadeau-Valle Mathieu
金额：
$1.27万
依托单位：
Universit de Montral
依托单位国家：
加拿大
项目类别：
Studentship Programs
财政年份：
2014
资助国家：
加拿大
项目状态：
已结题
起止时间：
2014-12-01 至 2015-12-01
来源：
https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=331286&lang=en
关键词：
Allosterism Functionnal Selectivity Immunology Inflammation Interleukin-1 Myometrium Pharmacology Preterm Birth Preterm Labor Reproduction

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中文摘要
翻译
炎症与早产(PTL)和足月分娩(TL)密切相关，与感染无关。包括IL-1在内的促炎细胞因子与子宫内子宫激活蛋白(UAP)的诱导有关，而子宫激活蛋白(UAP)在子宫内的作用
英文摘要
Inflammation is firmly linked to preterm labor (PTL) and term labor (TL) independently of the presence of infection. Pro-inflammatory cytokines including IL-1, are implicated in the induction of uterine activation proteins (UAP) within the uterus, which c
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Inhibiting Interleukin-1 receptor during pregnancy to prevent neonatal mortality and morbidity induced by placental/chorioamniotic inflammation
Inhibiting Interleukin-1 receptor during pregnancy to prevent neonatal mortality and morbidity induced by placental/chorioamniotic inflammation
  • 批准号：
    339562
  • 项目类别：
    Studentship Programs
  • 资助金额：
    $10.93万
  • 财政年份：
    2015
  • 负责人：
    Nadeau-Valle Mathieu
  • 依托单位：
    Universit de Montral