The role of the partitioning defective protein 6 (Par6) and phosphatidylinositide 3-kinases (PI3K) signaling axis in transforming growth factor beta tumour suppressor in breast cancer metastasis

分区缺陷蛋白 6 (Par6) 和磷脂酰肌醇 3-激酶 (PI3K) 信号轴在乳腺癌转移中转化生长因子 β 肿瘤抑制因子中的作用

• 批准号: 331364
• 负责人: Delroba Alham
• 金额: $ 1.27万
• 依托单位: University of Guelph
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-12-01 至 2015-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=331364&lang=en
• 关键词: Breast Cancer; Cell Polarity; Epithelial-Mesenchymal Transition In Metastasis; Inducing Appoptosis (Cell Death); Metastasis; Partitioning Defective Protein 6 (Par6); Phosphatidyl-Inositol-3-Kinase (Pi3k); Phsophorylation/ Activation Of Proteins; Polarity

The role of the Par6-PI3K signaling axis in TGFbeta tumour suppressor in breast cancer metastasis Metastasis, the dissemination of a tumour to distant sites, causes 90% of deaths by breast cancer. This is due to the inability of metastatic cancer cells t

Par 6-PI 3 K信号转导轴在TGF β肿瘤抑制因子中的作用 转移，即肿瘤向远处的扩散，导致90%的乳腺癌死亡。这是由于转移性癌细胞不能转移，