The chemerin effect on granulosa cell transcriptome study showed its role in the expression of three molecules associated with PCOS, the adrenergic receptor alpha 1, propiomelanocortin and adiponectin in rat.

凯莫瑞对颗粒细胞转录组的影响研究表明，其在大鼠体内与 PCOS 相关的三种分子（肾上腺素能受体 α1、丙黑皮质素和脂联素）的表达中发挥作用。

• 批准号: 324534
• 负责人: Nivet Anne-Laure
• 金额: $ 0.07万
• 依托单位: Ottawa Hospital Research Institute
• 依托单位国家: 加拿大
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-01-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=324534&lang=en
• 关键词: Chemerin; In Vitro Granulosa Primary Cell Culture; In Vivo Dht Treated Rat Pcos Model; Microarrays; Polycystic Ovarian Syndrome; Protein Assay; Qpcr

Polycystic Ovarian Syndrome (PCOS) affects 10 % of women in reproductive age and accounts for 75% of women who are unable to ovulate. It is associated with obesity, cardiovascular diseases and diabetes. In the ovary, it is associated with suppressed growt

多囊卵巢综合征（PCOS）影响10%的育龄妇女，占无法排卵妇女的75%。它与肥胖、心血管疾病和糖尿病有关。在卵巢中，它与抑制生长有关。