Advances in Computer Assisted Mosaic Arthroplasty

计算机辅助马赛克关节成形术的进展

基本信息

  • 批准号:
    121650-2012
  • 负责人:
  • 金额:
    $ 2.48万
  • 依托单位:
  • 依托单位国家:
    加拿大
  • 项目类别:
    Discovery Grants Program - Individual
  • 财政年份:
    2015
  • 资助国家:
    加拿大
  • 起止时间:
    2015-01-01 至 2016-12-31
  • 项目状态:
    已结题

项目摘要

Cartilage degeneration is a widespread problem which occurs predominantly in the knee, ankle, and shoulder. For younger, active patients, early cartilage replacement can result in a much improved quality of life and can delay or eliminate the eventual need for prosthetic joint replacement, with substantial savings to the Canadian healthcare system. Mosaic arthroplasty is a surgical procedure in which plugs of cartilage and bone are transplanted from non-load-bearing areas of the joint to the site of the cartilage defect. We have shown in previous research that computer-assisted mosaic arthroplasty (CAMA) results in better clinical outcomes than conventional mosaic arthroplasty. The proposed research, which will train four graduate and three undergraduate students, will develop computer algorithms and user interfaces to improve the delivery of CAMA in three areas: 1. Almost all computer-assisted operations involve a patient CT or MRI scan, followed by a pre-operative planning stage, followed by the operation. We will collapse the scanning and planning stages of CAMA into the operation itself: The surgeon will intraoperatively scan the cartilage surface with a tracked arthroscope probe, will use a planning algorithm to develop a surgical plan, and will execute the plan using computer tracking and guidance. This can reduce waiting times and can reduce patient exposure to ionizing radiation. 2. For arthroscopic CAMA, we will provide the surgeon with an augmented reality guidance display, where the surgical plan is superimposed on the live arthroscope video, shown on a display beside the patient. This will reduce the cognitive burden on the surgeon and may make the success of the operation more likely. 3. One method of CAMA tool guidance uses patient-specific guides, which are manufactured on a 3D printer; their bottom side fits tightly to the patient's cartilage surface and their top side contains holes to guide the surgical tools. We will develop a computer algorithm that designs the guides automatically, encoding the operator's hidden heuristic knowledge and saving substantial operator time over the current manual method.
软骨变性是一种普遍存在的问题,主要发生在膝关节、踝关节和肩部。对于年轻、活跃的患者,早期软骨置换可以大大提高生活质量,并可以延迟或消除最终对假体关节置换术的需求,为加拿大医疗保健系统节省大量资金。马赛克关节成形术是一种外科手术,将软骨和骨塞从关节的非承重区域移植到软骨缺损的部位。我们已经在之前的研究中表明,计算机辅助的马赛克关节置换术(CAMA)比传统的马赛克关节置换术有更好的临床效果。拟议的研究将培训四名研究生和三名本科生,将开发计算机算法和用户界面,以在三个方面改进CAMA的交付:

项目成果

期刊论文数量(0)
专著数量(0)
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Stewart, James其他文献

Hybrid adaptive radiotherapy with on-line MRI in cervix cancer IMRT
  • DOI:
    10.1016/j.radonc.2013.11.006
  • 发表时间:
    2014-02-01
  • 期刊:
  • 影响因子:
    5.7
  • 作者:
    Oh, Seungjong;Stewart, James;Cho, Young-Bin
  • 通讯作者:
    Cho, Young-Bin
Epidemiology and genomic analysis of Klebsiella oxytoca from a single hospital network in Australia.
  • DOI:
    10.1186/s12879-022-07687-7
  • 发表时间:
    2022-08-24
  • 期刊:
  • 影响因子:
    3.7
  • 作者:
    Stewart, James;Judd, Louise M.;Jenney, Adam;Holt, Kathryn E.;Wyres, Kelly L.;Hawkey, Jane
  • 通讯作者:
    Hawkey, Jane
Dosimetrically Triggered Adaptive Intensity Modulated Radiation Therapy for Cervical Cancer
Impact of Microcalcifications on Risk of Malignancy in Thyroid Nodules with Indeterminate or Benign Cytology
  • DOI:
    10.1177/0194599815605326
  • 发表时间:
    2016-01-01
  • 期刊:
  • 影响因子:
    3.4
  • 作者:
    Brophy, Catherine;Stewart, James;Sheahan, Patrick
  • 通讯作者:
    Sheahan, Patrick
Macromolecule extravasation-xenograft size matters: a systematic study using probe-based confocal laser endomicroscopy (pCLE).
  • DOI:
    10.1007/s11307-013-0641-z
  • 发表时间:
    2013-12
  • 期刊:
  • 影响因子:
    3.1
  • 作者:
    Dietrich, Antje;Stewart, James;Huether, Melanie;Helm, Mario;Schuetze, Christina;Schnittler, Hans-Joachim;Jaffray, David A.;Kunz-Schughart, Leoni A.
  • 通讯作者:
    Kunz-Schughart, Leoni A.

Stewart, James的其他文献

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{{ truncateString('Stewart, James', 18)}}的其他基金

Advances in Computer Assisted Mosaic Arthroplasty
计算机辅助马赛克关节成形术的进展
  • 批准号:
    121650-2012
  • 财政年份:
    2017
  • 资助金额:
    $ 2.48万
  • 项目类别:
    Discovery Grants Program - Individual
Software Development
软件开发
  • 批准号:
    499918-2016
  • 财政年份:
    2016
  • 资助金额:
    $ 2.48万
  • 项目类别:
    Experience Awards (previously Industrial Undergraduate Student Research Awards)
Advances in Computer Assisted Mosaic Arthroplasty
计算机辅助马赛克关节成形术的进展
  • 批准号:
    121650-2012
  • 财政年份:
    2014
  • 资助金额:
    $ 2.48万
  • 项目类别:
    Discovery Grants Program - Individual
Advances in Computer Assisted Mosaic Arthroplasty
计算机辅助马赛克关节成形术的进展
  • 批准号:
    121650-2012
  • 财政年份:
    2013
  • 资助金额:
    $ 2.48万
  • 项目类别:
    Discovery Grants Program - Individual
Advances in Computer Assisted Mosaic Arthroplasty
计算机辅助马赛克关节成形术的进展
  • 批准号:
    121650-2012
  • 财政年份:
    2012
  • 资助金额:
    $ 2.48万
  • 项目类别:
    Discovery Grants Program - Individual
Increasing tumoricidal response to radiation therapy with gold nanoparticles
使用金纳米粒子提高放射治疗的杀肿瘤反应
  • 批准号:
    389167-2010
  • 财政年份:
    2012
  • 资助金额:
    $ 2.48万
  • 项目类别:
    Alexander Graham Bell Canada Graduate Scholarships - Doctoral
New methods for articular cartilage repair through computer-assisted surgery
通过计算机辅助手术修复关节软骨的新方法
  • 批准号:
    385959-2010
  • 财政年份:
    2012
  • 资助金额:
    $ 2.48万
  • 项目类别:
    Collaborative Health Research Projects
New methods for articular cartilage repair through computer-assisted surgery
通过计算机辅助手术修复关节软骨的新方法
  • 批准号:
    385959-2010
  • 财政年份:
    2011
  • 资助金额:
    $ 2.48万
  • 项目类别:
    Collaborative Health Research Projects
Increasing tumoricidal response to radiation therapy with gold nanoparticles
使用金纳米粒子提高放射治疗的杀肿瘤反应
  • 批准号:
    389167-2010
  • 财政年份:
    2011
  • 资助金额:
    $ 2.48万
  • 项目类别:
    Alexander Graham Bell Canada Graduate Scholarships - Doctoral
Visualization and interfaces for computer-assisted surgery
计算机辅助手术的可视化和界面
  • 批准号:
    121650-2009
  • 财政年份:
    2011
  • 资助金额:
    $ 2.48万
  • 项目类别:
    Discovery Grants Program - Individual

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