MRI Acquisition and Analysis Methods for Image Guided Neurosurgery

图像引导神经外科的 MRI 采集和分析方法

• 批准号: 170426-2012
• 负责人: Pike, Bruce
• 金额: $ 3.79万
• 依托单位: University of Calgary
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=569579
• 关键词: MRI; Acquisition; Analysis; Methods; Image

Magnetic resonance imaging (MRI) is an exceptionally rich technology that enables probing of a myriad of brain tissue properties. In addition to revolutionizing diagnostic radiology, MRI has become a cornerstone in modern minimally invasive image-guided surgery where its detailed information improves surgical precision and safety while reducing total health care costs. The broad goal of this research program is the development of new MRI technologies for use in image-guided neurosurgery. More specifically, this proposal is focused on the development of technologies for planning deep brain stimulation; a treatment for disorders, such as Parkinson's disease, consisting of the surgical implantation of stimulation electrodes in specific structures of the brain. Our objectives are to develop MRI methods to precisely localize the stimulation targets, to map their neuronal connections to other brain structures, to image the cerebral blood vessels, and to integrate these data within a preoperative surgical planning software environment. Collectively, this work will advance the state-of-the-art in image-guided neurosurgery, making the procedure safer and more effective, while creating new tools and techniques with broad applications in diagnostic medical imaging and image-guided surgery.

磁共振成像(MRI)是一项非常丰富的技术，可以探测无数的脑组织属性。除了使诊断放射学发生革命性变化外，MRI还已成为现代微创图像引导手术的基石，其详细信息提高了手术的精度和安全性，同时降低了总的医疗保健成本。这项研究计划的广泛目标是开发用于图像引导神经外科的新MRI技术。更具体地说，这项提议的重点是开发计划脑深部刺激的技术；一种治疗帕金森氏症等疾病的方法，包括在大脑的特定结构中手术植入刺激电极。我们的目标是开发MRI方法来精确定位刺激目标，映射它们与其他大脑结构的神经元连接，成像脑血管，并将这些数据整合到手术前计划软件环境中。总而言之，这项工作将推动图像引导神经外科的最先进水平，使手术更安全和更有效，同时创造在诊断医学成像和图像引导外科中广泛应用的新工具和技术。