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Abrogation of Cancer Cell Extravasation in Renal Cell Carcinoma PDX lines via Invadopodia Dysregulation Mediated by PAK1 Inhibitors.

Abrogation of Cancer Cell Extravasation in Renal Cell Carcinoma PDX lines via Invadopodia Dysregulation Mediated by PAK1 Inhibitors.
通过 PAK1 抑制剂介导的侵入伪足失调消除肾细胞癌 PDX 系中的癌细胞外渗。
批准号:
324180
负责人:
Williams Karla
金额:
$0.07万
依托单位国家:
加拿大
项目类别:
财政年份:
2015
资助国家:
加拿大
项目状态:
已结题
起止时间:
2015-01-01 至 2016-01-01

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中文摘要
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英文摘要
For tumor cells to move through the body they need to be able to alter their physical environment. One way they are able to do this is via specialized structures called invadopodia. Invadopodia are unique to highly aggressive tumor cells and are sites of
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Development of a Liquid Biopsy for Early Breast Cancer Detection
  • 批准号:
    468110
  • 项目类别:
    Operating Grants
  • 资助金额:
    $4.37万
  • 财政年份:
    2022
  • 负责人:
    Williams Karla
  • 依托单位:
Canada Research Chair - Tier 2
  • 批准号:
    481091
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2022
  • 负责人:
    Williams Karla
  • 依托单位:
Characterization of invadopodia formation in response to local cues and their role in orchestrating metastasis.
  • 批准号:
    419125
  • 项目类别:
    Operating Grants
  • 资助金额:
    $55.17万
  • 财政年份:
    2020
  • 负责人:
    Williams Karla
  • 依托单位:
Canada Research Chair - Tier 2 - CIHR Funded
  • 批准号:
    384952
  • 项目类别:
  • 资助金额:
    $36.43万
  • 财政年份:
    2017
  • 负责人:
    Williams Karla
  • 依托单位:
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