Role of the intestinal epithelial insulin-like growth factor-1 receptor in the intestinal growth effects of glucagon-like peptide-2

肠上皮胰岛素样生长因子1受体在胰高血糖素样肽2肠道生长效应中的作用

• 批准号: 182318
• 负责人: Trivedi Shivangi
• 金额: $ 0.22万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Summer Student Programs
• 财政年份: 2009
• 资助国家: 加拿大
• 起止时间: 2009-02-01 至 2009-06-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=182318&lang=en
• 关键词: Glp-2; Growth; Igf-1 Receptor; Intestine; Knockout Mice

We have previously shown that the intestinal growth factor GLP-2 requires the presence of the IGF-1 receptor somewhere in the whole body. We are now examining whether this receptor is required to be present in the intestinal cells that are directly involv

我们以前已经表明，肠道生长因子GLP-2需要IGF-1受体在整个身体的某个地方的存在。我们现在正在研究这种受体是否需要存在于直接参与的肠细胞中。